Fatty acids in triglycerides (TG) are the
major source of energy in the body. TG are
stored in adipocytes or are found in dietary
fat.
40% of daily energy requirement of people
in industrial countries is met with TG.
Main tissues using fatty acids as energy
source are liver, heart and resting skeletal
muscle
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الثلاثاء، 5 مايو 2015
lipid Metabolism
Building Blocks for phospholipids and
Glycolipids.
2. Fatty acids are fuel molecules.
3. Fatty acids derivatives serve as hormones
and intracellular messengers.
4. Fatty acids can be attached to protein and
targeted them to membrane locations.
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High level of ketone bodies in blood are referred to as ketonemia •More ketone bodies in the urine is called as ketonuria. •Lungs mainly eliminate acetone. •The acetyl CoA formed in fatty acid oxidation enters into TCA cycle only if fat and carbohydrate degradation are appropriately balanced
High level of ketone bodies in blood are referred
to as ketonemia
•More ketone bodies in the urine is called as
ketonuria.
•Lungs mainly eliminate acetone.
•The acetyl CoA formed in fatty acid oxidation
enters into TCA cycle only if fat and carbohydrate
degradation are appropriately balanced
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الجمعة، 10 أبريل 2015
Digestion & absorption
Lipids: Definition
A group of organic substances that are
insoluble in water and polar compounds
but are soluble in organic solvents such as
ether, benzene, alcohol and choloroform
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Gluconeogenesis
Average adult human uses 160-200 g/day of
glucose, mostly in the brain (75%)
About 20g glucose in body fluids
About 190 g stored as glycogen
Less than 2 days worth
In addition to eating glucose, we also make it.
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الأحد، 15 مارس 2015
Fate of Absorbed Glucose 1stPriority: glycogen storage◦ Stored in muscle and liver 2ndPriority: provide energy◦ Oxidized to ATP 3rdPriority: stored as fat◦ Only excess glucose ◦ Stored as triglycerides in adipose
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الثلاثاء، 30 ديسمبر 2014
TCA _ مقررات المستوى الثالث كليه الطب _ Biochemistry
The Three Stages of Respiration
• Stage I All the fuel molecules are oxidized to
acetyl-CoA.
• Stage II :Acetyl-CoA is completely oxidized into CO2
electrons are collected by NAD and FAD via the electrons are collected by NAD and FAD via the
citric acid cycle.
• Stage III Passage of electrons through the electron
transport system to yield ATP from oxidative
phosphorylation
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